James B McMahon Selected Research

2- (4- ((4- amino- 2- methylphenyl)diazenyl)phenylsulfonyl)ethanesulfonoperoxoic acid

3/2009

A selective small-molecule nuclear factor-kappaB inhibitor from a high-throughput cell-based assay for "activator protein-1 hits".

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James B McMahon Research Topics

Disease

14	Neoplasms (Cancer) 01/2018 - 09/2002
9	Infections 01/2015 - 09/2002
4	Hypoxia (Hypoxemia) 04/2015 - 09/2006
4	Renal Cell Carcinoma (Grawitz Tumor) 08/2012 - 09/2006
2	Ewing Sarcoma (Sarcoma, Ewing) 05/2016 - 06/2011
2	Colonic Neoplasms (Colon Cancer) 01/2016 - 11/2014
2	Carcinoma (Carcinomatosis) 11/2014 - 04/2013
2	Neurofibromatosis 1 (Neurofibromatosis Type I) 02/2014 - 01/2013
2	Carcinogenesis 09/2012 - 09/2006
1	Malaria 01/2018
1	Adenocarcinoma of Lung 01/2017
1	Astrocytoma (Pilocytic Astrocytoma) 11/2015
1	Virus Diseases (Viral Diseases) 12/2014
1	Hepatocellular Carcinoma (Hepatoma) 08/2013
1	Kidney Neoplasms (Kidney Cancer) 09/2012
1	Melanoma (Melanoma, Malignant) 07/2011
1	Sarcoma (Soft Tissue Sarcoma) 06/2011
1	Leukemia 06/2011
1	Genetic Translocation (Chromosomal Translocation) 06/2011
1	Breast Neoplasms (Breast Cancer) 03/2009
1	Type I Syndactyly 07/2006
1	Severe Acute Respiratory Syndrome 07/2006
1	Acquired Immunodeficiency Syndrome (AIDS) 03/2005
1	Lymphoid Leukemia 09/2002

Drug/Important Bio-Agent (IBA)

6	Proteins (Proteins, Gene)FDA Link 01/2018 - 09/2006
4	Biological ProductsIBA 01/2017 - 09/2011
4	Transcription Factors (Transcription Factor)IBA 04/2015 - 09/2006
4	Griffithsia griffithsin proteinIBA 01/2015 - 07/2006
3	Pharmaceutical PreparationsIBA 01/2018 - 02/2011
3	Antiviral Agents (Antivirals)IBA 01/2015 - 03/2005
3	Anti-Infective Agents (Microbicides)IBA 01/2015 - 03/2005
3	LectinsIBA 01/2015 - 02/2012
3	AlkaloidsIBA 11/2014 - 02/2014
3	PhytochemicalsIBA 02/2014 - 01/2013
2	DNA (Deoxyribonucleic Acid)IBA 05/2016 - 07/2006
2	LuciferasesIBA 01/2016 - 01/2012
2	Oxygen (Dioxygen)IBA 04/2015 - 04/2011
2	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 01/2012 - 02/2007
1	madecassic acidIBA 01/2018
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2017
1	englerin AIBA 05/2016
1	EWS-FLI fusion proteinIBA 05/2016
1	makaluvamine FIBA 01/2016
1	discorhabdin HIBA 01/2016
1	discorhabdin WIBA 01/2016
1	discorhabdin LIBA 01/2016
1	discorhabdin BIBA 01/2016
1	Molecular Probes (Molecular Probe)IBA 04/2015
1	Hypoxia-Inducible Factor 1IBA 04/2015
1	Viral RNAIBA 12/2014
1	Guanidine (Guanidine Nitrate)FDA Link 08/2014
1	mirabilin GIBA 08/2014
1	Sirolimus (Rapamycin)FDA Link 04/2014
1	4- (5- acetyloxy- 8,8- dimethyl- 6- (3- methylbut- 2- en- 1- yl)- 4- oxo- 4,8- dihydropyrano(2,3- f)chromen- 3- yl)- 1,2- phenylene diacetateIBA 04/2014
1	Ribosomal Protein S6 Kinases (S6 Kinase)IBA 04/2014
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 04/2014
1	QuassinsIBA 02/2014
1	LignansIBA 02/2014
1	Epithelial Cell Adhesion MoleculeIBA 08/2013
1	Ether (Diethyl Ether)IBA 04/2013
1	drimaneIBA 04/2013
1	TetralonesIBA 04/2013
1	SesquiterpenesIBA 04/2013
1	N- (3- amino- 1- (cyclobutylmethyl)- 2,3- dioxopropyl)- 3- (2- ((((1,1- dimethylethyl)amino)carbonyl)amino)- 3,3- dimethyl- 1- oxobutyl)- 6,6- dimethyl- 3- azabicyclo(3.1.0)hexan- 2- carboxamideIBA 01/2013
1	telaprevirIBA 01/2013
1	NucleosidesIBA 01/2013
1	Protease Inhibitors (Protease Inhibitor)IBA 01/2013
1	Ribavirin (Virazole)FDA LinkGeneric 01/2013
1	Interferon-alpha (Interferon Alfa)IBA 01/2013
1	muconomycin AIBA 08/2012
1	Protein Synthesis InhibitorsIBA 08/2012
1	Mannose (D-Mannose)IBA 02/2012
1	Polysaccharides (Glycans)IBA 02/2012
1	DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN)IBA 02/2012
1	cyanovirin NIBA 02/2012
1	CucurbitacinsIBA 01/2012
1	Complex MixturesIBA 01/2012
1	Apoptosis Regulatory ProteinsIBA 09/2011
1	tedanolideIBA 07/2011
1	Plicamycin FDA Link 06/2011
1	CarubicinIBA 01/2011
1	NF-kappa B (NF-kB)IBA 03/2009
1	matrigelIBA 03/2009
1	2- (4- ((4- amino- 2- methylphenyl)diazenyl)phenylsulfonyl)ethanesulfonoperoxoic acidIBA 03/2009
1	endothelial PAS domain-containing protein 1IBA 09/2006
1	Amino Acids FDA Link 07/2006
1	Adenosine Triphosphate (ATP)IBA 03/2006
1	Cytotoxins (Cytolysins)IBA 03/2006
1	Peptides (Polypeptides)IBA 06/2004
1	Protein Kinase CIBA 09/2002
1	pedilstatinIBA 09/2002
1	Growth InhibitorsIBA 09/2002

Therapy/Procedure

2	Therapeutics 04/2014 - 02/2007
1	Subcutaneous Injections 12/2014